• 05 JUN 20
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    Embryo Implantation

    Embryo Implantation

    By IVF Serum’s Embryologist, Aggeliki Fega Sometimes, the process of the embryo transfer is confused with implantation. During an embryo transfer, the embryo under ultrasound guidance and via a soft catheter is placed inside the uterus, generally 1 to 2 cm from the top of the uterine cavity. Implantation is the incident that hopefully will

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    • 05 JUN 20
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    ROS & Oxidative Stress

    ROS & Oxidative Stress

    By IVF Serum’s embryologist Dimitra Poulou Reactive oxygen species (ROS) are normal by-products of the metabolism and small amounts of them are required for specific cellular processes of the spermatozoon such as capacitation, acrosome reaction, and the acquisition of the hyperactivated state. When generated in excess, ROS are commonly known to negatively affect germ cell

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    • 24 APR 20
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    Smoking & DNA fragmentation in human sperm

    Smoking & DNA fragmentation in human sperm

    By Aggeliki Fegga – Embryologist What is DNA Fragmentation? DNA Fragmentation is observed in cells undergoing apoptosis (programmed cell death). DNA is cleaved by a specific protein during the latter stages of the cell’s self-destruction process. What are the causes of DNA Fragmentation in spermatozoa? Spermatozoa are highly differentiated cells, that have lost most of

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    • 24 APR 20
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    What is the human blastocyst?

    What is the human blastocyst?

    By  Galia Tsangkalova – Embryologist, Lab Director Human blastocyst is an embryo on its 5th day of development. It consists of 24 up to 322 cells, its size is about 0.2mm and its discrete parts are: the trophectoderm (TE), the inner cell mass (ICM) and the blastocoel. All these structures are surrounded by zona pellucida

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    • 24 APR 20
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    Blastocyst grading system

    Blastocyst grading system

    By Galia Tsangkalova – Embryologist, Lab Director The most commonly used blastocyst grading system is the one proposed by Gardner and Schoolcraft. Every blastocyst is graded by using one number and two letters. The number indicates the expansion level which results from the comparison of the blastocoel cavity to the volume of the embryo. The

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    • 24 APR 20
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    Activation of Human Gametes

    Activation of Human Gametes

    by Galia Tsangkalova (Embryologist, Lab Director) Fertilization is the process in which the male gamete (spermatozoon) fuses together with the female gamete (oocyte) in order to form the zygote. A prerequisite for fertilization to take place is that both gametes must be activated first. Sperm activation Sperm activation is naturally induced by environmental factors and

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